State Grants

Colorado Small Business Grants & Funding Programs

Colorado's Office of Economic Development and International Trade (OEDIT) coordinates state funding programs for small businesses. The state's strong startup ecosystem, particularly in Denver and Boulder, offers additional opportunities.

136grants available
From state agencies, SBA & local programs

OEDIT Programs

OEDIT administers various programs including the Advanced Industries Accelerator Grants, AI Accelerator Program, and Rural Jump-Start grants for businesses in rural Colorado communities.

Colorado SBDC Network

The Colorado Small Business Development Center Network provides free consulting and helps businesses access SBA loans, grants, and state funding programs throughout Colorado.

Denver & Boulder Programs

Denver offers the Small Business Investment Fund and various neighborhood programs. Boulder has strong support for technology and climate-focused startups through local initiatives.

Colorado Business Grants

136 grants found

upcoming
US Economic Development Administration

Build to Scale Program

The Build to Scale Program provides funding to support entrepreneurship and innovation

VariesNationwideRolling
All SectorsBusiness Growth
open
First Peoples Fund

Yégo Action Grant

Provides up to $2,500 in quick-response funding for Native artists and culture bearers who need support to sustain their creative endeavors due to emergencies or unanticipated expenses.

Up to $2,500NationwideInvalid Date
Creative & HeritageBusiness Support
rolling
First Peoples Fund

Yéego Action Grant

The Yéego Action Grant provides quick-response funding for Native artists and culture bearers who need support to sustain their creative endeavors due to emergencies or unanticipated expenses.

Up to $2,500NationwideInvalid Date
Creative & HeritageInnovation & R&D
open
U.S. National Institutes of Health (NIH)

U.S. National Institutes of Health Grants

The NIH is currently funding grant opportunities related to COVID-19 research.

VariesNationwideInvalid Date
Life Sciences & HealthInnovation & R&D
upcoming
Breva

Breva Thrive Grant

The Breva Thrive Grant awards $5,000 each quarter to small business owners who are making a measurable difference in their local communities.

$5,000Nationwide1 Apr 2026
All SectorsBusiness Support
upcoming
Founders First CDC

2026 Pride Fund for LGBTQIA+ Business Owners

The 2026 Pride Fund for LGBTQIA+ Business Owners provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U.S.

$1,000Nationwide1 Apr 2026
All SectorsCommunity & Social
upcoming
Visionaries

Hey Helen Grant

The Hey Helen Grant offers $10,000 in unrestricted funding to support women and nonbinary entrepreneurs building mission-driven, for-profit businesses in the U.S.

$10,000Nationwide30 Apr 2026
All SectorsBusiness Support
open
U.S. Department of the Treasury

Work Opportunity Tax Credit (WOTC)

The WOTC is a federal tax credit that encourages companies to hire employees from groups who have historically faced significant barriers to gainful employment.

VariesNationwide31 Dec 2025
All SectorsBusiness Support
open
National Institutes of Health

Cancer Intervention and Surveillance Modeling Network (CISNET) (U01 Clinical Trial Not Allowed)

The National Institutes of Health is accepting applications for grants to support cancer intervention and surveillance modeling.

Up to $1,240,000Nationwide12 Feb 2026
Life Sciences & HealthInnovation & R&D
open
National Endowment for the Arts

NEA Grants for Arts Projects 1, FY 2027

The National Endowment for the Arts is accepting applications for grants to support arts projects.

$10,000 - $100,000Nationwide12 Feb 2026
All SectorsBusiness Support
open
National Institutes of Health

Limited Competition: Competing Revisions to Support Clinical Trials in Somatic Cell Genome Editing (U19 Clinical Trial Required)

The National Institutes of Health is accepting applications for grants to support clinical trials in somatic cell genome editing.

VariesNationwide13 Feb 2026
Life Sciences & HealthInnovation & R&D
open
National Institutes of Health

Enhancing Reuse of NHGRI Data Assets (R03 Clinical Trial Not Allowed)

The National Institutes of Health is accepting applications for grants to support the reuse of data assets.

Up to $125,000Nationwide15 Feb 2026
Life Sciences & HealthInnovation & R&D
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Frequently Asked Questions

Common questions about business grants in Colorado