Massachusetts Small Business Grants & Funding Programs
Massachusetts supports startups, life sciences companies, manufacturers, and neighborhood businesses through statewide innovation programs and local business assistance.
Statewide Growth Programs
Massachusetts businesses can access business growth support, financing, and technical assistance through statewide public and quasi-public partners.
Innovation and Life Sciences Support
Boston and the broader innovation ecosystem provide strong support for technology, biotech, climate, and research-led startups through accelerators and public-private programs.
Local and Corridor Programs
Boston, Worcester, Springfield, and other communities offer local small business grants, corridor support, and entrepreneur assistance for eligible firms.
Massachusetts Business Grants
145 grants found
U.S. National Institutes of Health Grants
The NIH is currently funding grant opportunities related to COVID-19 research.
Breva Thrive Grant
The Breva Thrive Grant awards $5,000 each quarter to small business owners who are making a measurable difference in their local communities.
2026 Pride Fund for LGBTQIA+ Business Owners
The 2026 Pride Fund for LGBTQIA+ Business Owners provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U.S.
Hey Helen Grant
The Hey Helen Grant offers $10,000 in unrestricted funding to support women and nonbinary entrepreneurs building mission-driven, for-profit businesses in the U.S.
Work Opportunity Tax Credit (WOTC)
The WOTC is a federal tax credit that encourages companies to hire employees from groups who have historically faced significant barriers to gainful employment.
Cancer Intervention and Surveillance Modeling Network (CISNET) (U01 Clinical Trial Not Allowed)
The National Institutes of Health is accepting applications for grants to support cancer intervention and surveillance modeling.
NEA Grants for Arts Projects 1, FY 2027
The National Endowment for the Arts is accepting applications for grants to support arts projects.
Limited Competition: Competing Revisions to Support Clinical Trials in Somatic Cell Genome Editing (U19 Clinical Trial Required)
The National Institutes of Health is accepting applications for grants to support clinical trials in somatic cell genome editing.
Enhancing Reuse of NHGRI Data Assets (R03 Clinical Trial Not Allowed)
The National Institutes of Health is accepting applications for grants to support the reuse of data assets.
REQUEST FOR INFORMATION – MUTUALLY BENEFICIAL MULTIDISCIPLINARY INNOVATION ECOSYSTEMS
The Dept of the Army -- Materiel Command is accepting applications for requests for information to support innovation ecosystems.
Ocean Technology and Interdisciplinary Coordination
The U.S. National Science Foundation is accepting applications for grants to support ocean technology and interdisciplinary coordination.
Physical Oceanography
The U.S. National Science Foundation is accepting applications for grants to support physical oceanography research.
Frequently Asked Questions
Common questions about business grants in Massachusetts