State Grants

Massachusetts Small Business Grants & Funding Programs

Massachusetts supports startups, life sciences companies, manufacturers, and neighborhood businesses through statewide innovation programs and local business assistance.

177grants available
From state agencies, SBA & local programs

Statewide Growth Programs

Massachusetts businesses can access business growth support, financing, and technical assistance through statewide public and quasi-public partners.

Innovation and Life Sciences Support

Boston and the broader innovation ecosystem provide strong support for technology, biotech, climate, and research-led startups through accelerators and public-private programs.

Local and Corridor Programs

Boston, Worcester, Springfield, and other communities offer local small business grants, corridor support, and entrepreneur assistance for eligible firms.

Massachusetts Business Grants

177 grants found

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Massachusetts Technology Collaborative (MassTech)

Massachusetts Manufacturing Accelerate Program (MMAP)

Invests in small- to medium-sized manufacturers to help coordinate and prepare our supply chain to respond to increasing demands and to spur new opportunities for growth.

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ManufacturingInnovation & R&D
open
Massachusetts Life Sciences Center (MLSC)

Massachusetts Next Generation Initiative (MassNextGen)

A competitive program that awards women-led early-stage life science companies a year-long customized package of support, which includes non-dilutive grant funding and access to a network of seasoned Executive Coaches from the life sciences ecosystem to refine their business strategies and effectively raise capital.

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Life Sciences & HealthInnovation & R&D
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Massachusetts Life Sciences Center (MLSC)

Life Sciences NIIMBL

Accelerates biopharmaceutical manufacturing innovation, supports the development of standards that enable more efficient and rapid manufacturing capabilities, and educates and trains a world-leading biopharmaceutical manufacturing workforce, fundamentally advancing U.S. competitiveness in this industry.

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Life Sciences & HealthInnovation & R&D
open
Massachusetts Life Sciences Center (MLSC)

Building Breakthroughs (Biomanufacturing)

Provides grants for capital projects that support biomanufacturing innovation, including improvements to upstream/downstream processing, production of cell and gene therapies, monoclonal antibodies, and small molecules, quality and safety, and storage/stability, in the Commonwealth.

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Life Sciences & HealthInnovation & R&D
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Massachusetts Life Sciences Center (MLSC)

Novel Therapeutics Delivery

Aims to foster the development of novel technologies and techniques for the delivery of existing or innovative therapies by working at the intersection of engineering, biology, chemistry, and medicine.

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Life Sciences & HealthInnovation & R&D
open
Massachusetts Life Sciences Center (MLSC)

Women's Health

Supports collaborative projects that aim to improve the discovery, technical innovation, and/or analysis of datasets to answer pressing life science questions around women’s health.

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Life Sciences & HealthInnovation & R&D
open
Massachusetts Life Sciences Center (MLSC)

Bits to Bytes

Provides grants for scientific projects that generate and analyze large datasets to answer pressing life science questions, and to attract and train data scientists in the Commonwealth.

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Life Sciences & HealthInnovation & R&D
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Massachusetts Life Sciences Center (MLSC)

Life Sciences Tax Incentives

The Tax Incentive program is offered to companies engaged in life sciences research and development, commercialization and manufacturing in Massachusetts.

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Life Sciences & HealthInnovation & R&D
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Massachusetts Life Sciences Center (MLSC)

Research Infrastructure Program

Provides grants for capital projects that support the life sciences ecosystem in Massachusetts by enabling and supporting life sciences research and development in the Commonwealth.

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Life Sciences & HealthInnovation & R&D
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MassVentures

SBIR Target Technologies (START) Program

Helps high growth companies expand local employment opportunities, promote local manufacturing and commercialization, and stimulate innovation across the Commonwealth.

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TechnologyInnovation & R&D
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MGCC, Empowering Small Business

Empower Digital Grant Program

The Empower Digital Grant is a match grant awarded to small businesses in Massachusetts that seek to improve their business’s digital capabilities. The Empower Digital Grant Program is a grant program that provides funding to small businesses in Massachusetts to support their digital transformation.

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All SectorsDigital & Technology
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MGCC

Biz-M-Power Crowdfunding Program

The Biz-M-Power crowdfunding matching grant program offers small businesses in Massachusetts financial assistance with their acquisition, expansion, improvement or lease of a facility, purchase or lease of equipment, or with meeting other capital needs for the business.

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All SectorsBusiness Support
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Frequently Asked Questions

Common questions about business grants in Massachusetts