US Grant Types

Innovation & R&D Business Grants

Innovation and R&D grants support businesses developing new products, services, and processes. From early-stage prototyping to advanced technology development, there are funding programmes to accelerate your innovation journey.

51grants available

Product & Technology Development

Grants are available for developing new products, improving existing ones, and adopting emerging technologies. These programmes often fund proof-of-concept work, prototyping, and pilot projects.

Collaborative Research

Many R&D grants encourage partnerships between businesses and universities or research institutions. Collaborative projects can access larger funding pools and specialist expertise.

Commercialisation Support

Moving from research to market-ready products requires investment. Commercialisation grants help bridge the gap between lab and launch, funding trials, regulatory compliance, and market testing.

US Innovation & R&D Grants

51 grants found

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U.S. Small Business Administration

SBIR/STTR programs

Grants for small business innovation research

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All SectorsInnovation & R&D
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Empire State Development

Innovation Matching Grants Program

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All SectorsInnovation & R&D
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SBA

Research and Development Grants

Fund a diverse portfolio of startups and small businesses across technology areas and markets to stimulate technological innovation, meet Federal research and development (R&D) needs, and increase commercialization to transition R&D into impact.

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All SectorsInnovation & R&D
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SBA

Federal and State Technology (FAST) Partnership Program

This is a one-year funding opportunity for organizations to execute state/regional programs that increase the number of SBIR (innovation)/STTR (research and development) proposals; increase the number of SBIR/STTR awards; and better prepare SBIR/STTR awardees for commercial success.

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All SectorsInnovation & R&D
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U.S. Economic Development Administration

Research and National Technical Assistance (RNTA)

The RNTA program funds research, evaluation, and national technical assistance projects that promote competitiveness and innovation in distressed rural and urban regions throughout the United States and its territories.

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All SectorsInnovation & R&D
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SBA

Small Business Technology Transfer (STTR)

The STTR program encourages scientific research that helps meet federal research and development objectives, with high potential for commercialization.

VariesNationwideRolling
All SectorsInnovation & R&D
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SBA

Small Business Innovation Research (SBIR)

The SBIR program encourages scientific research that helps meet federal research and development objectives, with high potential for commercialization.

Up to $1.8 millionNationwideRolling
All SectorsInnovation & R&D
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First Peoples Fund

Yéego Action Grant

The Yéego Action Grant provides quick-response funding for Native artists and culture bearers who need support to sustain their creative endeavors due to emergencies or unanticipated expenses.

Up to $2,500NationwideInvalid Date
Creative & HeritageInnovation & R&D
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U.S. National Institutes of Health (NIH)

U.S. National Institutes of Health Grants

The NIH is currently funding grant opportunities related to COVID-19 research.

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Life Sciences & HealthInnovation & R&D
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National Institutes of Health

Cancer Intervention and Surveillance Modeling Network (CISNET) (U01 Clinical Trial Not Allowed)

The National Institutes of Health is accepting applications for grants to support cancer intervention and surveillance modeling.

Up to $1,240,000Nationwide12 Feb 2026
Life Sciences & HealthInnovation & R&D
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National Institutes of Health

Limited Competition: Competing Revisions to Support Clinical Trials in Somatic Cell Genome Editing (U19 Clinical Trial Required)

The National Institutes of Health is accepting applications for grants to support clinical trials in somatic cell genome editing.

VariesNationwide13 Feb 2026
Life Sciences & HealthInnovation & R&D
open
National Institutes of Health

Enhancing Reuse of NHGRI Data Assets (R03 Clinical Trial Not Allowed)

The National Institutes of Health is accepting applications for grants to support the reuse of data assets.

Up to $125,000Nationwide15 Feb 2026
Life Sciences & HealthInnovation & R&D

Frequently Asked Questions

Common questions about innovation & r&d grants