State Grants

Pennsylvania Small Business Grants & Funding Programs

Pennsylvania offers strong support for small businesses through the Department of Community and Economic Development (DCED) and Ben Franklin Technology Partners. Philadelphia and Pittsburgh have additional local programs.

140grants available
From state agencies, SBA & local programs

DCED Programs

DCED offers various programs including the Pennsylvania Industrial Development Authority loans, First Industries Fund for agriculture, and Keystone Innovation Zone tax credits.

Ben Franklin Technology Partners

Ben Franklin provides funding for technology companies including seed and early-stage investments, business incubation, and connections to venture capital throughout Pennsylvania.

City Programs

Philadelphia offers programs through the Philadelphia Industrial Development Corporation. Pittsburgh has various initiatives through regional development agencies and innovation districts.

Pennsylvania Business Grants

140 grants found

open
First Peoples Fund

YΓ©go Action Grant

Provides up to $2,500 in quick-response funding for Native artists and culture bearers who need support to sustain their creative endeavors due to emergencies or unanticipated expenses.

Up to $2,500NationwideInvalid Date
Creative & HeritageBusiness Support
rolling
First Peoples Fund

YΓ©ego Action Grant

The YΓ©ego Action Grant provides quick-response funding for Native artists and culture bearers who need support to sustain their creative endeavors due to emergencies or unanticipated expenses.

Up to $2,500NationwideInvalid Date
Creative & HeritageInnovation & R&D
open
U.S. National Institutes of Health (NIH)

U.S. National Institutes of Health Grants

The NIH is currently funding grant opportunities related to COVID-19 research.

VariesNationwideInvalid Date
Life Sciences & HealthInnovation & R&D
upcoming
Breva

Breva Thrive Grant

The Breva Thrive Grant awards $5,000 each quarter to small business owners who are making a measurable difference in their local communities.

$5,000Nationwide1 Apr 2026
All SectorsBusiness Support
upcoming
Founders First CDC

2026 Pride Fund for LGBTQIA+ Business Owners

The 2026 Pride Fund for LGBTQIA+ Business Owners provides $1,000 microgrants to 20 LGBTQIA+-owned small businesses across the U.S.

$1,000Nationwide1 Apr 2026
All SectorsCommunity & Social
upcoming
Visionaries

Hey Helen Grant

The Hey Helen Grant offers $10,000 in unrestricted funding to support women and nonbinary entrepreneurs building mission-driven, for-profit businesses in the U.S.

$10,000Nationwide30 Apr 2026
All SectorsBusiness Support
open
U.S. Department of the Treasury

Work Opportunity Tax Credit (WOTC)

The WOTC is a federal tax credit that encourages companies to hire employees from groups who have historically faced significant barriers to gainful employment.

VariesNationwide31 Dec 2025
All SectorsBusiness Support
open
National Institutes of Health

Cancer Intervention and Surveillance Modeling Network (CISNET) (U01 Clinical Trial Not Allowed)

The National Institutes of Health is accepting applications for grants to support cancer intervention and surveillance modeling.

Up to $1,240,000Nationwide12 Feb 2026
Life Sciences & HealthInnovation & R&D
open
National Endowment for the Arts

NEA Grants for Arts Projects 1, FY 2027

The National Endowment for the Arts is accepting applications for grants to support arts projects.

$10,000 - $100,000Nationwide12 Feb 2026
All SectorsBusiness Support
open
National Institutes of Health

Limited Competition: Competing Revisions to Support Clinical Trials in Somatic Cell Genome Editing (U19 Clinical Trial Required)

The National Institutes of Health is accepting applications for grants to support clinical trials in somatic cell genome editing.

VariesNationwide13 Feb 2026
Life Sciences & HealthInnovation & R&D
open
National Institutes of Health

Enhancing Reuse of NHGRI Data Assets (R03 Clinical Trial Not Allowed)

The National Institutes of Health is accepting applications for grants to support the reuse of data assets.

Up to $125,000Nationwide15 Feb 2026
Life Sciences & HealthInnovation & R&D
open
Dept of the Army -- Materiel Command

REQUEST FOR INFORMATION – MUTUALLY BENEFICIAL MULTIDISCIPLINARY INNOVATION ECOSYSTEMS

The Dept of the Army -- Materiel Command is accepting applications for requests for information to support innovation ecosystems.

VariesNationwide15 Feb 2026
All SectorsInnovation & R&D
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Frequently Asked Questions

Common questions about business grants in Pennsylvania