South Carolina Small Business Grants & Funding Programs
South Carolina supports small businesses through statewide commerce and innovation partners, local development agencies, and entrepreneur programs serving coastal, manufacturing, and service-based businesses.
Statewide Commerce Support
South Carolina businesses can access support aimed at expansion, job creation, and business growth through statewide commerce and development partners.
Innovation and Research Programs
Startup and innovation-led businesses can pursue commercialization support, founder programs, and research-linked initiatives through statewide and regional partners.
Charleston, Columbia, and Regional Support
Charleston, Columbia, Greenville, and other communities offer local business support, corridor programs, and entrepreneur initiatives for eligible firms.
South Carolina Business Grants
140 grants found
Ocean Technology and Interdisciplinary Coordination
The U.S. National Science Foundation is accepting applications for grants to support ocean technology and interdisciplinary coordination.
Physical Oceanography
The U.S. National Science Foundation is accepting applications for grants to support physical oceanography research.
FY 2026 Notice of Funding Opportunity: Infrastructure Investment and Jobs Act (IIJA) FAA Contract Tower (FCT) Competitive Grant Program
The Airport Improvement Program Discretionary Grants is accepting applications for grants to support contract tower competitive grants.
Biological Oceanography
The U.S. National Science Foundation is accepting applications for grants to support biological oceanography research.
NSF Dynamic Language Infrastructure - NEH Documenting Endangered Languages
The U.S. National Science Foundation is accepting applications for grants to support language infrastructure and documentation.
Rauschenberg Medical Emergency Grant
Provides up to $5,000 in funding to artists experiencing recent, unexpected medical, dental, or mental health emergencies.
Zoom Solopreneur 50
A national recognition program supporting independent entrepreneurs who are shaping the future of work.
Intuit QuickBooks x Mailchimp Small Business Hero Program
The Intuit QuickBooks and Mailchimp Small Business Hero Program awards $20,000 grants to U.S. small businesses with owners aged 18 or older that show courage, perseverance, and integrity.
Dare To Post Challenge
The Dare To Post Challenge offers a $100,000 prize pool split evenly among eligible creators who complete a 30-day daily posting challenge on Instagram.
Cultivate Small Business
Santander's Cultivate Small Business program is a free, 12-week virtual training initiative designed to support early-stage food entrepreneurs, with a focus on underserved founders in low- to moderate-income communities.
The UPS Store Small Biz Challenge
The 2026 UPS Store Small Biz Challenge offers entrepreneurs the chance to win a grand prize, including a cash award from the $35,000 prize pool and a spotlight in Inc. magazine.
The Mott Million Dollar Challenge
The Mott Million Dollar Challenge is a national pitch competition offering a share of $1 million in prizes to support innovative, real-world problem-solving ideas created by students in grades K–12.
Frequently Asked Questions
Common questions about business grants in South Carolina